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KMID : 1034720170090010012
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Journal of Neurosonology and Neuroimaging
2017 Volume.9 No. 1 p.12 ~ p.17
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Relationship between 10-year Cardiovascular Risk and Carotid Intima-media Thickness in Medical Check-up Participants
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Kim Kwang-Hyun
Yoon Hye-Rin
Kim Hye-Weon
Nam Hyo-Suk
Han Sang-Won
Kim Jeong-Yeon
Park Jae-Hyun
Yu Hyun-Jeung
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Abstract
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Background: To assess the relationship between 10-year cardiovascular risk and carotid intima-media thickness (IMT) in medical check-up participants.
Methods: The participants who underwent a medical check-up were enrolled into this study. Adults aged 50 to 69 years were eligible if they did not have a history of atherosclerotic cardiovascular disease (ASCVD) or stroke. The 10-year CVD risk was calculated using the ASCVD risk estimator (http://tools.acc.org/ASCVD-Risk-Estimator). For the study, the maximum IMT of both carotid arteries were measured and the mean value of them was used for analysis.
Results: A total of 265 participants were enrolled in this study. The mean age was 58 years, and 28% of the participants were women. The mean IMT was significantly correlated with the 10-year CVD risk in all participants (r=0.180, p=0.003). Among men, the mean IMT was 0.81±0.13 mm and 64 (33.5%) participants had ≥10% 10-year CVD risk. There was significant difference in the mean IMT between ≥10% 10-year CVD risk group and <10% 10-year CVD risk group (p=0.025). With women, the mean IMT was 0.78±0.10 mm and 6 (8.1%) participants had ≥10% 10-year CVD risk. No significant difference was observed in the mean IMT between the groups (p=0.291).
Conclusions: Whilst routine sonographic screening for carotid artery stenosis has little supporting evidence, our study suggested that there may be an opportunity for decreasing the rate of CVD and stroke through the tailored sonographic examination in high risk subjects.
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KEYWORD
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Cardiovascular disease, Carotid intima-media thickness, Primary prevention, Doppler ultrasonography
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